A Frequency Translation System for Multi-Channel, Multi-Nuclear MR Spectroscopy. Academic Article uri icon


  • OBJECTIVE: Most MRI scanners are equipped to receive signals from 1H array coils but few support multi-channel reception for other nuclei. Using receive arrays can provide significant SNR benefits, usually exploited to enable accelerated imaging, but the extension of these arrays to non-1H nuclei has received less attention because of the relative lack of broadband array receivers. Non-1H nuclei often have low sensitivity and stand to benefit greatly from the increase in SNR that arrays can provide. This paper presents a cost-effective approach for adapting standard 1H multi-channel array receivers for use with other nuclei - in this case, 13C. METHODS: A frequency translation system has been developed that uses active mixers residing at the magnet bore to convert the received signal from a non-1H array to the 1H frequency for reception by the host system receiver. RESULTS: This system has been demonstrated at 4.7T and 7T while preserving SNR and isolation. 1H decoupling, particularly important for 13C detection, can be straightforwardly accommodated. CONCLUSION: Frequency translation can convert 1H-only multi-channel receivers for use with other nuclei while maintaining SNR and channel isolation while still enabling 1H decoupling. SIGNIFICANCE: This work allows existing multi-channel MRI receivers to be adapted to receive signals from nuclei other than 1H, allowing for the use of receive arrays for in vivo multi-nuclear NMR.

published proceedings

  • IEEE Trans Biomed Eng

author list (cited authors)

  • Ogier, S. E., Wilcox, M., Cheshkov, S., Dimitrov, I. E., Malloy, C. R., McDougall, M. P., & Wright, S. M.

citation count

  • 4

complete list of authors

  • Ogier, Stephen E||Wilcox, Matthew||Cheshkov, Sergey||Dimitrov, Ivan E||Malloy, Craig R||McDougall, Mary P||Wright, Steven M

publication date

  • January 2021