Sweet-MXene hydrogel with mixed-dimensional components for biomedical applications. Academic Article

abstract

• Biodegradable hydrogels are promising extracellular matrix-like materials for biomedical applications due to their high compatibility, ease of administration and minimal invasion. The injectable hydrogels to be considered for regenerative therapies should mimic the intrinsic properties of tissues, i.e. self-healing and swelling. Here, we present facile electrically conductive sweet-MXene (S-MXene) hydrogel with novel mixed-dimensional compositions including natural zero dimensional (0D) fluorescent carbon dots in honey, delaminated 2D fluorescent titanium carbide (Ti3C2) nanosheets and bioinspired 3D crosslinked polymeric chitosan networks. The developed versatile (Ti3C2-MXene-honey-chitosan) heterostructure exhibited excellent porous architecture with desired swelling and controlled degradation. This electrically conductive composite is highly biocompatible, it supported cell attachment and survival.

authors

• Amiri, Ahmad

published proceedings

• J Mech Behav Biomed Mater

author list (cited authors)

• Rafieerad, A., Sequiera, G. L., Yan, W., Kaur, P., Amiri, A., & Dhingra, S.

citation count

• 25

complete list of authors

• Rafieerad, Alireza||Sequiera, Glen Lester||Yan, Weiang||Kaur, Parminder||Amiri, Ahmad||Dhingra, Sanjiv

publication date

• January 2020

publisher

• Elsevier  Publisher

published in

• Journal of the Mechanical Behavior of Biomedical Materials  Journal

keywords

• Biocompatible Composite
• Biocompatible Materials
• Carbon
• Cell Adhesion
• Cell Line
• Cell Survival
• Chitosan
• Electrically Conductive Hydrogel
• Fluorescent Dyes
• Humans
• Hydrogels
• Materials Testing
• Nanostructures
• Porous Hydrogel
• Stem Cells
• Ti(3)c(2) Mxene Nanosheets
• Titanium

Digital Object Identifier (DOI)

• 10.1016/j.jmbbm.2019.103440

start page

• 103440

end page

• 103440

volume

• 101

URL

• http://dx.doi.org/10.1016/j.jmbbm.2019.103440