Drug-polymer conjugates coupled to a peptidic carrier Patent uri icon

abstract

  • Monodisperse macromolecular conjugate compositions of a peptidic carrier irreversibly or reversibly conjugated with one or more effectors and one or more therapeutic agents, wherein at least one effector or therapeutic agent is attached to a pendant reactive group on said peptidic carrier via a water-soluble polymer. Monodispersity is obtained through the use of orthogonal and separate conjugation reactions.

author list (cited authors)

  • Sinko, P. J., Stein, S., Gunaseelan, S., Pooyan, S., Wan, L. i., & Zhang, X.

complete list of authors

  • Sinko, Patrick J||Stein, Stanley||Gunaseelan, Simi||Pooyan, Shahriar||Wan, Li||Zhang, Xiaoping

publication date

  • December 2010