Mass spectrometry distinguishing C=C location and cis/trans isomers: A strategy initiated by water radical cations. Academic Article

abstract

• We present an approach for the elucidation of C=C bond position and cis/trans isomers, which is achieved by the reaction of ambient water radical cations and double bonds, followed by the fragmentation of epoxide radical cations to generate diagnostic ions in tandem mass spectrometry. Hexenol double bond positional isomers and cis/trans isomers which exhibit different properties and biological functions are characterized as a proof of concept. The merits of the approach include the simplicity of experimental setup, rapid derivatization (within seconds), the obviation of organic solvents, as well as easy spectral interpretation.

authors

• Yan, Xin

published proceedings

• Anal Chim Acta

altmetric score

• 2.6

author list (cited authors)

• Zhang, X., Ren, X., Chingin, K., Xu, J., Yan, X., & Chen, H.

citation count

• 6

complete list of authors

• Zhang, Xiaoping||Ren, Xiang||Chingin, Konstantin||Xu, Jiaquan||Yan, Xin||Chen, Huanwen

publication date

• January 2020

publisher

• Elsevier  Publisher

published in

• Analytica Chimica Acta  Journal

keywords

• Ambient Corona Discharge Ionization Mass Spectrometry
• Carbon-carbon Double Bond
• Cis/trans Isomers
• Positional Isomers
• Water Radical Cations

Digital Object Identifier (DOI)

• 10.1016/j.aca.2020.09.027

start page

• 146

end page

• 154

volume

• 1139

URL

• http://dx.doi.org/10.1016/j.aca.2020.09.027