Comparative Study on Production of Antibody in Broilers Vaccinated with Four Lyophilized Newcastle Disease Vaccine
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A comparative efficacy of four lyophilized Newcastle disease vaccine, namely, Medivac ND-LaSota, BCRDV, Izovac B1 Hitchner and Cevac Vitapest-L in regard to the production of Himagglutination Inhibition (HI)- antibody was accomplished. For this, a total of 75 chicks were equally divided into five experimental groups such as, A, B, C, D and E. The HI antibody titers of group A vaccinated on 5 and 21 days of age with Medivac NDLaSota fluctuated among the Mean SD of 89.60 33.05, 102.40 33.05 and 192 67.46 at 15 (10 DPV), 19 (14 DPV) and 31 (26 DPV) days of age respectively. As regards, group B administered with BCRDV on the same days, the HI titers varied with the Mean SD of 83.20 30.91, 102.40 33.04 and 204.80 66.09 at 15 (10 DPV), 19 (14 DPV) and 31 (26 DPV) days of age respectively. When considered the HI antibody titers of group C inoculated with Izovac B1 Hitchner on days 5 and 21 of age, HI titer exhibited the Mean SD of 80.00 43.33, 96.00 33.73 and 192.00 67.46 at 15 (10 DPV), 19 (14 DPV) and 31 (26 DPV) days of age respectively. Elucidation of HI antibody titers of group D birds receiving Cevac Vitapest-L on same days were recorded to be of Mean SD of 96.00 33.73, 115.20 26.98 and 320.00 173.31 at 15 (10 DPV), 19 (14 DPV) and 31 (26 DPV) days of age respectively. In birds of unvaccinated control group E, HI titers were found to be ranged from 32- 64, 16-32, 8-16, 4-8 and 2-4 with Mean SD of 48.00 16.87, 24.00 8.43, 11.20 4.13, 5.20 1.93 and 3.40 0.97 on 3, 15, 17, 19 and 31 days of age respectively. Thus, it was found that birds of group A, B, C and D vaccinated with Medivac ND-LaSota, BCRDV, Izovac B1 Hitchner and Cevac Vitapest-L induced slightly higher level of HI antibody titers than that of BCRDV. Maternally derived antibody (MDA) persisted to a minimal level until the age of chicks of day 17 and later on MDA declined. Keywords: Vaccine; Antibody Titer; Newcastle Disease VirusDOI: http://dx.doi.org/10.3329/bjm.v27i1.9159 BJM 2010; 27(1): 1-5
