Fast detection of a protozoan pathogen, Perkinsus marinus, using AlGaN/GaN high electron mobility transistors Academic Article uri icon

abstract

  • Antibody-functionalized, Au-gated AlGaN/GaN high electron mobility transistors (HEMTs) were used to detect Perkinsus marinus. The antibody was anchored to the gate area through immobilized thioglycolic acid. The AlGaN/GaN HEMT drain-source current showed a rapid response of less than 5 s when the infected solution was added to the antibody-immobilized surface. The sensor can be recycled with a phosphate buffered saline wash. These results clearly demonstrate the promise of field-deployable electronic biological sensors based on AlGaN/GaN HEMTs for Perkinsus marinus detection.

published proceedings

  • APPLIED PHYSICS LETTERS

author list (cited authors)

  • Wang, Y., Chu, B. H., Chen, K. H., Chang, C. Y., Lele, T. P., Papadi, G., ... Ren, F.

citation count

  • 25

complete list of authors

  • Wang, Yu-Lin||Chu, BH||Chen, KH||Chang, CY||Lele, TP||Papadi, G||Coleman, JK||Sheppard, BJ||Dungen, CF||Pearton, SJ||Johnson, JW||Rajagopal, P||Roberts, JC||Piner, EL||Linthicum, KJ||Ren, F

publication date

  • June 2009