Fast Detection of Perkinsus Marinus, a Prevalent Pathogen of Oysters and Clams from Sea Waters Academic Article uri icon

abstract

  • AbstractAntibody-functionalized, Au-gated AlGaN/GaN high electron mobility transistors (HEMTs) were used to detect Perkinsus marinus. The antibody was anchored to the gate area through immobilized thioglycolic acid. The AlGaN/GaN HEMT were grown by a molecular beam epitaxy system (MBE) on sapphire substrates. Infected sea waters were taken from the tanks in which Tridacna crocea infected with P. marinus were living and dead. The AlGaN/GaN HEMT showed a rapid response of drain-source current in less than 5 seconds when the infected sea waters were added to the antibody-immobilized surface. The recyclability of the sensors with wash buffers between measurements was also explored. These results clearly demonstrate the promise of field-deployable electronic biological sensors based on AlGaN/GaN HEMTs for Perkinsus marinus detection.

published proceedings

  • MRS Advances

author list (cited authors)

  • Wang, Y., Chu, B. H., Chen, K. H., Chang, C., Lele, T. P., Papadi, G., ... Ren, F.

citation count

  • 0

complete list of authors

  • Wang, Yu-Lin||Chu, BH||Chen, KH||Chang, Chih-Yang||Lele, Tanmay P||Papadi, George||Coleman, James K||Sheppard, Barbara J||Dungan, Chris F||Pearton, SJ||Johnson, JW||Ren, F

publication date

  • January 2009