A comparative genomics multitool for scientific discovery and conservation. Academic Article uri icon

abstract

  • The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of whichall but 9 arepreviously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than80% of mammalian families. We find that regions of reduced genetic diversity are more abundant in species at a high risk of extinction, discern signals of evolutionary selection at high resolution and provide insights from individual reference genomes. By prioritizing phylogenetic diversity and making data available quickly and without restriction, the Zoonomia Project aims to support biological discovery, medical research and the conservation of biodiversity.

published proceedings

  • Nature

altmetric score

  • 465.098

author list (cited authors)

  • Zoonomia Consortium.

citation count

  • 90

complete list of authors

publication date

  • January 2020

published in