Meta-analysis of polyploid cotton QTL shows unequal contributions of subgenomes to a complex network of genes and gene clusters implicated in lint fiber development. Academic Article uri icon

abstract

  • QTL mapping experiments yield heterogeneous results due to the use of different genotypes, environments, and sampling variation. Compilation of QTL mapping results yields a more complete picture of the genetic control of a trait and reveals patterns in organization of trait variation. A total of 432 QTL mapped in one diploid and 10 tetraploid interspecific cotton populations were aligned using a reference map and depicted in a CMap resource. Early demonstrations that genes from the non-fiber-producing diploid ancestor contribute to tetraploid lint fiber genetics gain further support from multiple populations and environments and advanced-generation studies detecting QTL of small phenotypic effect. Both tetraploid subgenomes contribute QTL at largely non-homeologous locations, suggesting divergent selection acting on many corresponding genes before and/or after polyploid formation. QTL correspondence across studies was only modest, suggesting that additional QTL for the target traits remain to be discovered. Crosses between closely-related genotypes differing by single-gene mutants yield profoundly different QTL landscapes, suggesting that fiber variation involves a complex network of interacting genes. Members of the lint fiber development network appear clustered, with cluster members showing heterogeneous phenotypic effects. Meta-analysis linked to synteny-based and expression-based information provides clues about specific genes and families involved in QTL networks.

published proceedings

  • Genetics

altmetric score

  • 3

author list (cited authors)

  • Rong, J., Feltus, F. A., Waghmare, V. N., Pierce, G. J., Chee, P. W., Draye, X., ... Paterson, A. H.

citation count

  • 204

complete list of authors

  • Rong, Junkang||Feltus, F Alex||Waghmare, Vijay N||Pierce, Gary J||Chee, Peng W||Draye, Xavier||Saranga, Yehoshua||Wright, Robert J||Wilkins, Thea A||May, O Lloyd||Smith, C Wayne||Gannaway, John R||Wendel, Jonathan F||Paterson, Andrew H

publication date

  • June 2007