Two-dimensional metal organic frameworks for biomedical applications. Academic Article uri icon


  • Two-dimensional (2D) metal organic frameworks (MOFs), are an emerging class of layered nanomaterials with well-defined structure and modular composition. The unique pore structure, high flexibility, tunability, and ability to introduce desired functionality within the structural framework, have led to potential use of MOFs in biomedical applications. This article critically reviews the application of 2D MOFs for therapeutic delivery, tissue engineering, bioimaging, and biosensing. Further, discussion on the challenges and strategies in next generation of 2D MOFs are also included. This article is categorized under: Nanotechnology Approaches to Biology > Nanoscale Systems in Biology.

published proceedings

  • Wiley Interdiscip Rev Nanomed Nanobiotechnol

altmetric score

  • 4.5

author list (cited authors)

  • Arun Kumar, S., Balasubramaniam, B., Bhunia, S., Jaiswal, M. K., Verma, K., Prateek, .., ... Gaharwar, A. K.

citation count

  • 22

complete list of authors

  • Arun Kumar, Shreedevi||Balasubramaniam, Bhuvaneshwari||Bhunia, Sukanya||Jaiswal, Manish K||Verma, Kartikey||Khademhosseini, Ali||Gupta, Raju Kumar||Gaharwar, Akhilesh K

publication date

  • March 2021