Serendipity strikes again—efficient preparation of lithium tetramethylcuprate(iii) via rapid injection NMR Academic Article uri icon


  • Lithium tetramethylcuprate(III), Me(4)CuLi, the Cu(III) analog of the Gilman reagent, has been prepared in high yield from halo-Gilman reagents Me(2)CuLi.LiX (X = Cl, Br, I) and 2,3-dichloropropene and found to have surprising thermal stability. The cyano-Gilman reagent (X = CN) follows a different pathway.

author list (cited authors)

  • Bartholomew, E. R., Bertz, S. H., Cope, S. K., Murphy, M. D., Ogle, C. A., & Thomas, A. A.

citation count

  • 39

publication date

  • January 2010