Striking Similarities between CDRs in Some mAbs That Neutralize COVID-19. Academic Article uri icon


  • Four of five different monoclonal antibodies (mAbs) that have been crystallized in complex with the receptor binding domain (RBD) of the SARS-CoV-2 spike protein (S) have remarkably similar primary and secondary loop structures at the heavy chain complementarity-determining regions (HCDR) 1 and 2. All these reports give a structural basis for the deceptively difficult problem of accurate peptidomimetic loop mimic design.

published proceedings

  • ACS Med Chem Lett

altmetric score

  • 3

author list (cited authors)

  • Mi, T., & Burgess, K.

citation count

  • 3

complete list of authors

  • Mi, Tianxiong||Burgess, Kevin

publication date

  • September 2020