Implant-based repair of osteochondral defects
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The present invention is directed to a unique technology for preparing a growth-factor free, cylindrical, hydrogel implant that has multiple (three or more) longitudinal hydrogel zones with varying chemical and physical properties. The implant may be wholly made of hydrogels or the hydrogels may be associated with cells, such as mesenchymal stem cells (MSCs).
author list (cited authors)
Grunlan, M. A., Hahn, M. S., & Saunders, W. B.