Feasibility of Using a 1T Extremity Scanner with a Four-Element Array to Detect 31P in the Human Calf. Conference Paper uri icon

abstract

  • The feasibility of conducting in vivo non-localized skeletal muscle 31P Magnetic Resonance Spectroscopy (MRS) with a low-cost extremity 1 Tesla magnet is demonstrated. We designed and built a transmit-only quadrature birdcage, four-element receive coil array, and employed a home-built spectrometer interfaced with a commercial ONI 1.0T magnet. In phantom comparison tests with a large loop coil of comparable size, the array was found to improve the SNR by a factor of 1.8 and the linewidth from 0.72 ppm to 0.45 ppm. Phantom and in vivo testing results show only 6 averages with a 4 second repetition time are required to obtain quantifiable 31P spectra. Initial in vivo human skeletal muscle 31P spectra successfully allowed for peak characterization. A low-cost approach to MRS could enable more widespread use of this tool in clinical diagnosis and in vivo metabolic research.

name of conference

  • 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

published proceedings

  • Annu Int Conf IEEE Eng Med Biol Soc

altmetric score

  • 0.25

author list (cited authors)

  • Carrell, T., Gu, M., McDougall, M. P., & Wright, S. M.

citation count

  • 1

complete list of authors

  • Carrell, Travis||Gu, Minyu||McDougall, Mary P||Wright, Steven M

publication date

  • July 2019