A high-throughput microfluidic light controlling platform for biofuel producing photosynthetic microalgae analysis Conference Paper uri icon


  • We have developed a high-throughput microalgae screening platform capable of analyzing biomass production at different light conditions with single colony resolution. Combinations of different light intensities and day-night cycles resulting in 64 light conditions for each of 64 culture compartments were implemented on a single microfluidic chip by blocking the light from a single light source with different black color dye concentrations and by switching between water and black color dye, respectively. Five microalgae colony-trapping structures in each culture compartment allowed single-colony resolution growth and biofuel-production analysis. Oil-producing microalgae, Botryococcus braunii, were successfully cultured and characterized using this screening system.

published proceedings

  • 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010

author list (cited authors)

  • Kim, H. S., Weiss, T. L., Devarenne, T. P., & Han, A.

complete list of authors

  • Kim, HS||Weiss, TL||Devarenne, TP||Han, A

publication date

  • December 2010