Amphetamine actions in dorsolateral tegmental rats: Hypodipsia, anorexia, and central nervous system permeation to [14C]amphetamine Academic Article uri icon

abstract

  • Electrolytic lesions of the dorsolateral tegmentum produced hyperdipsia, enhanced amphetamine-induced hypodipsia, yet attenuated amphetamine-induced anorexia. Central nervous system permeation by [14C]amphetamine was comparable in control, operated control, and tegmental rats. These data suggest that (a) a common motivational process, such as malaise, cannot explain the anorexic and hypodipsic properties of amphetamine and (b) that the influence of tegmental damage on amphetamine actions did not result from differences in brain amphetamine levels. © 1982 Academic Press, Inc.

author list (cited authors)

  • Wellman, P. J., Clark, D. E., Rogers, J. K., & Thomas, J. C.

citation count

  • 2

publication date

  • May 1982