Amphetamine actions in dorsolateral tegmental rats: hypodipsia, anorexia, and central nervous system permeation to [14C] amphetamine.

abstract

• Electrolytic lesions of the dorsolateral tegmentum produced hyperdipsia, enhanced amphetamine-induced hypodipsia, yet attenuated amphetamine-induced anorexia. Central nervous system permeation by [14C]amphetamine was comparable in control, operated control, and tegmental rats. These data suggest that (a) a common motivational process, such as malaise, cannot explain the anorexic and hypodipsic properties of amphetamine and (b) that the influence of tegmental damage on amphetamine actions did not result from differences in brain amphetamine levels. 1982 Academic Press, Inc.

authors

• Wellman, Paul

published proceedings

• Behav Neural Biol

author list (cited authors)

• Wellman, P. J., Clark, D. E., Rogers, J. K., & Thomas, J. C.

citation count

• 2

complete list of authors

• Wellman, PJ||Clark, DE||Rogers, JK||Thomas, JC

publication date

• January 1982

publisher

• Elsevier  Publisher

published in

• Behavioral and Neural Biology  Journal

keywords

• Animals
• Blood-Brain Barrier
• Brain
• Dextroamphetamine
• Dose-Response Relationship, Drug
• Drinking
• Female
• Hunger
• Muridae
• Rats
• Tegmentum Mesencephali

Digital Object Identifier (DOI)

• 10.1016/s0163-1047(82)91292-4

start page

• 64

end page

• 69

volume

• 35

issue

• 1

URL

• http://dx.doi.org/10.1016/s0163-1047(82)91292-4