Hyperinsulinemia and obesity in the dorsolateral tegmental rat. Academic Article

abstract

• Adult female rats (N = 26) were prepared with either sham lesions or electrolytic lesions of the dorsolateral tegmentum (DLT). Body weight gain, adiposity, 72-hour food intake and day/night food intake, serum glucose and serum insulin levels were measured 15 and 17 days post-operatively. Dorsolateral tegmental lesions produced moderate weight gains and enhanced adiposity as assessed by the Lee Index. Although dorsolateral tegmental rats were hyperphagic only at night, hyperinsulinemia was observed during the day and the night. Hyperinsulinemia may contribute to the obesifying action of tegmental lesions in rats fed high-fat diets.

authors

• Wellman, Paul

published proceedings

• Physiol Behav

author list (cited authors)

• Wellman, P. J., Elissalde, M., Watkins, P. A., & Pinto, A.

citation count

• 2

complete list of authors

• Wellman, PJ||Elissalde, M||Watkins, PA||Pinto, A

publication date

• January 1984

publisher

• Elsevier  Publisher

published in

• Physiology and Behavior  Journal

keywords

• Animals
• Blood Glucose
• Body Weight
• Brain
• Eating
• Female
• Insulin
• Obesity
• Rats
• Rats, Inbred Strains
• Tegmentum Mesencephali

Digital Object Identifier (DOI)

• 10.1016/0031-9384(84)90060-x

start page

• 1

end page

• 4

volume

• 32

issue

• 1

URL

• http://dx.doi.org/10.1016/0031-9384(84)90060-x