EFFECTS OF SURGICAL REMOVAL OF INTERSCAPULAR BROWN ADIPOSE-TISSUE ON FOOD-INTAKE AND AMPHETAMINE ANOREXIA
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Adult male albino rats underwent surgical removal of interscapular brown adipose tissue (IBATX) or sham surgery. After recovery from surgery, daily 60-min feeding tests were conducted to evaluate the potential effect of IBATX on amphetamine anorexia. d-Amphetamine sulfate, at 1.0, 2.0, and 4.0 mg/kg (ip), induced dose-dependent but comparable anorexia in both IBATX and sham-surgery control rats. The implications of these data for the notion that amphetamine induces satiety, in part, via stimulation of BAT thermogenesis are discussed. 1984, The psychonomic Society, Inc.. All rights reserved.