Effects of surgical removal of interscapular brown adipose tissue on food intake and amphetamine anorexia Academic Article uri icon

abstract

  • Adult male albino rats underwent surgical removal of interscapular brown adipose tissue (IBATX) or sham surgery. After recovery from surgery, daily 60-min feeding tests were conducted to evaluate the potential effect of IBATX on amphetamine anorexia. d-Amphetamine sulfate, at 1.0, 2.0, and 4.0 mg/kg (ip), induced dose-dependent but comparable anorexia in both IBATX and sham-surgery control rats. The implications of these data for the notion that amphetamine induces satiety, in part, via stimulation of BAT thermogenesis are discussed. © 1984, The psychonomic Society, Inc.. All rights reserved.

author list (cited authors)

  • Wellman, P. J., & Watkins, P. A.

citation count

  • 1

publication date

  • November 1984