INFLUENCE OF FLUID DEPRIVATION LEVEL ON THE EXTINCTION OF CONDITIONED TASTE-AVERSION INDUCED BY AMPHETAMINE IN FEMALE RATS
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abstract
The present experiment examined the influence of differential fluid deprivation (8.5- or 23.5-h) on the extinction of amphetamine (2.0 mg/kg)-induced conditioned taste aversion in female rats. In two-bottle preference tests, rats trained and extinguished under a 23.5-h fluid-deprivation schedule displayed significantly faster extinction of saccharin taste aversion relative to that observed in rats trained and extinguished under an 8.5-h deprivation schedule. The more rapid extinction of amphetamine aversion observed in fluid-deprived rats is comparable to that described previously for conventional emetic punishers such as lithium chloride or cyclophosphamide. 1981, Psychonomic Society, Inc.. All rights reserved.