The role of nitric oxide in apoptosis. Academic Article

abstract

• Nitric oxide (NO) has been shown to play important roles in modulating cell viability. Both proapoptotic and antiapoptotic functions of NO have been reported. This article discusses our current understanding on the mechanisms responsible for the dual actions of NO in regulating apoptosis and propose that one common mechanism for NO-mediated inhibition of apoptosis is the inhibition of caspases via nitrosylation.

authors

• Li, Jianrong

published proceedings

• Semin Perinatol

author list (cited authors)

• Li, J., & Billiar, T. R.

citation count

• 27

complete list of authors

• Li, J||Billiar, TR

publication date

• February 2000

publisher

• Elsevier  Publisher

published in

• Seminars in Perinatology  Journal

keywords

• Animals
• Apoptosis
• Humans
• Nitric Oxide

PubMed Central ID

• 10709859

Digital Object Identifier (DOI)

• 10.1016/s0146-0005(00)80055-5

start page

• 46

end page

• 50

volume

• 24

issue

• 1

URL

• http://dx.doi.org/10.1016/s0146-0005(00)80055-5