Using soluble polymer supports to facilitate homogeneous catalysis. Academic Article uri icon

abstract

  • A review of various research studies conducted since 2002 on the use of soluble polymer supports to facilitate homogeneous catalysis is presented. TEMPO is a commonly used organocatalyst for the selective oxidation of primary alcohols to aldehydes. Use of PEG-supported proline as a catalyst is described in enantioselective conjugate addition reactions. A phosphonium salt is described and is found to deliver catalyzed formation of cyclic carbonates, while intermediate cyclic carbonates could be used without isolation as a phosgene-equivalent. The synthesis of three types of PEG-supported salen ligands could be used to catalyze the addition of diethyl zinc to aldehydes. A study including the use of PEG supports to prepare a tartate ester library is an effort to probe the effect of tartrate structure on stereoselectivity in Sharpless asymmetric epoxidation of allylic alcohols.

published proceedings

  • Chem Rev

altmetric score

  • 3

author list (cited authors)

  • Bergbreiter, D. E., Tian, J., & Hongfa, C.

citation count

  • 319

complete list of authors

  • Bergbreiter, David E||Tian, Jianhua||Hongfa, Chayanant

publication date

  • February 2009