Phosphorus-31 NMR relaxation studies of diethyl p-methoxyphenyl phosphate bound to phosphotriesterase Academic Article

abstract

• The effect of Mn2+ Mn2+, Mn2+ Zn2+ and Mn2+ Cd2+ reconstituted phosphotriesterase on the 31P spin lattice ( 1 T1) relaxation rate of diethyl p-methoxyphenyl phosphate has been investigated. In the presence of Mn2+ Mn2+ phosphotriesterase, the spin lattice relaxation rate of the phosphorus atom is enhanced giving an upper limit for the phosphorus-metal root mean-sixth average distance of 4.2 . These results demonstrate for the first time that substrates for phosphotriesterase bind in close proximity to the binuclear metal center. 1995.

authors

• Raushel, Frank

published proceedings

• BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

author list (cited authors)

• Mullins, L. S., Chae, M. Y., & Raushel, F. M.

citation count

• 2

complete list of authors

• Mullins, LS||Chae, MY||Raushel, FM

publication date

• December 1995

publisher

• Elsevier  Publisher

keywords

• 34 Chemical Sciences
• 3402 Inorganic Chemistry

Digital Object Identifier (DOI)

• 10.1016/0960-894X(95)00539-7

start page

• 3067

end page

• 3072

volume

• 5

issue

• 24