Asymmetric synthesis of 3-phenyl-2,3-methanophenylalanine developed by panning catalysts in a library format
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Optimal catalysts for the key cyclopropanation step in a synthesis of the title compound were identified by screening libraries of metal complex-ligand combinations; the synthesis was completed, and a derivative of the final product was crystallized to establish its solid state conformation.
author list (cited authors)
Moye-Sherman, D., Welch, M. B., Reibenspies, J., & Burgess, K.