Asymmetric synthesis of 3-phenyl-2,3-methanophenylalanine developed by panning catalysts in a library format Academic Article uri icon

abstract

  • Optimal catalysts for the key cyclopropanation step in a synthesis of the title compound were identified by screening libraries of metal complex-ligand combinations; the synthesis was completed, and a derivative of the final product was crystallized to establish its solid state conformation.

author list (cited authors)

  • Moye-Sherman, D., Welch, M. B., Reibenspies, J., & Burgess, K.

citation count

  • 26

publication date

  • January 1998