Solid‐Phase Syntheses of Unnatural Biopolymers Containing Repeating Urea Units Academic Article uri icon


  • New “oligourea”‐based peptidomimetics are the subject of this communication. Two new derivatives of this type, including the Leu‐enkephalin analog 1, have been prepared by addition of suitably protected isocyanates to amino acids supported on Rink's amide resin. The chemistry described is designed for solid‐phase approaches to combinatorial libraries by split syntheses. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

altmetric score

  • 9

author list (cited authors)

  • Burgess, K., Shin, H., & Linthicum, D. S.

citation count

  • 138

publication date

  • May 1995