SOLID-PHASE SYNTHESES OF UNNATURAL BIOPOLYMERS CONTAINING REPEATING UREA UNITS
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abstract
New oligoureabased peptidomimetics are the subject of this communication. Two new derivatives of this type, including the Leuenkephalin analog 1, have been prepared by addition of suitably protected isocyanates to amino acids supported on Rink's amide resin. The chemistry described is designed for solidphase approaches to combinatorial libraries by split syntheses. (Figure Presented.) Copyright 1995 by VCH Verlagsgesellschaft mbH, Germany