Chiral 1,3-cyclobutane amino acids: Syntheses and extended conformations Academic Article uri icon

abstract

  • Optically active samples of the N-protected 1,3-cyclobutane amino acids 1 and 2 were prepared from α-pinene. The synthesis of 1 is enantiodivergent insofar as both optical antipodes of the product can be prepared from the same α-pinene enantiomer. Single crystal X-ray diffraction studies of derivatives of 1 reveal these compounds can have extended conformations.

altmetric score

  • 3

author list (cited authors)

  • Burgess, K., Li, S., & Rebenspies, J.

citation count

  • 25

publication date

  • March 1997