Stereochemical Implications on Diversity in β-Turn Peptidomimetic Libraries
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Stereoisomers of compound 1 were prepared, and their preferred solution- phase conformations (in DMSO) were determined by a combination of NMR, CD, and molecular simulation approaches. It was shown that the stereochemistry of the pseudo i + 2 residue is the predominant consideration.
author list (cited authors)
Feng, Y., Pattarawarapan, M., Wang, Z., & Burgess, K.