Application of novel phosphine oxazoline ligands in asymmetric allylations of 4-acyloxy-2-pentene derivatives
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A library of novel phosphine oxazoline ligands 2 was tested in the asymmetric allylation of 4-acyloxy-2-pentenes 1. High throughput screening techniques were employed to accelerate this process. The data accumulated allowed the extent of asymmetric induction to be correlated with the ligand substituent R and ligand-to-metal ratios.
author list (cited authors)
Burgess, K., & Porte, A. M.