2,3-methanoamino acid analogs of Arg stabilize secondary structures of a 13 amino acid peptide in aqueous solution Academic Article uri icon

abstract

  • Peptidomimetics 1 and 2 of RN24 (an RNase A C-peptide analog) in which the ArgMO residue is replaced by 2R.3Scyclo-Arg and by 2S,3S-cyclo-Arg, respectively, show less temperature dependence in CD studies than the parent peptide.

published proceedings

  • CHEMICAL COMMUNICATIONS

author list (cited authors)

  • Lim, D., Moye-Sherman, D., Ham, I., Jim, S., Scholtz, J. M., & Burgess, K.

citation count

  • 11

complete list of authors

  • Lim, D||Moye-Sherman, D||Ham, I||Jim, S||Scholtz, JM||Burgess, K

publication date

  • November 1998