2,3-Methanoamino acid analogs of Arg stabilize secondary structures of a 13 amino acid peptide in aqueous solution Academic Article uri icon

abstract

  • Peptidomimetics 1 and 2 of RN24 (an RNase A C-peptide analog) in which the ArgMO residue is replaced by 2R.3Scyclo-Arg′ and by 2S,3S-cyclo-Arg′, respectively, show less temperature dependence in CD studies than the parent peptide.

author list (cited authors)

  • Lim, D., Moye-Sherman, D., Ham, I., Jin, S., Burgess, K., & Scholtz, J. M.

citation count

  • 10

publication date

  • January 1998