THE IMPORTANCE OF PHOSPHINE-TO-RHODIUM RATIOS IN ENANTIOSELECTIVE HYDROBORATIONS

abstract

• Catalyzed hydroborations of several 1,1-disubstituted aryl alkenes were studied. Formation of tertiary alcohols (after oxidation) was favored when high phosphine-to-rhodium ratios were used. Enantioselective variants of this process can give chiral primary and tertiary alcohols with different enantioselectivities indicative of mechanistic differences. Measurements of product optical yields as a function of optical purities of the catalyst gave a linear correlation. The mechanistic implications of these data are discussed. 1994.

authors

• Burgess, Kevin

published proceedings

• INORGANICA CHIMICA ACTA

author list (cited authors)

• BURGESS, K., & VANDERDONK, W. A.

citation count

• 9

complete list of authors

• BURGESS, K||VANDERDONK, WA

publication date

• June 1994

publisher

• Elsevier  Publisher

published in

• Inorganica Chimica Acta  Journal

keywords

• Catalysis
• Enantioselectivity
• Hydroboration
• Phosphine Complexes
• Rhodium Complexes

Digital Object Identifier (DOI)

• 10.1016/0020-1693(94)03860-0

start page

• 93

end page

• 98

volume

• 220

issue

• 1-2

URL

• http://dx.doi.org/10.1016/0020-1693(94)03860-0