The importance of phosphine-to-rhodium ratios in enantioselective hydroborations Academic Article uri icon


  • Catalyzed hydroborations of several 1,1-disubstituted aryl alkenes were studied. Formation of tertiary alcohols (after oxidation) was favored when high phosphine-to-rhodium ratios were used. Enantioselective variants of this process can give chiral primary and tertiary alcohols with different enantioselectivities indicative of mechanistic differences. Measurements of product optical yields as a function of optical purities of the catalyst gave a linear correlation. The mechanistic implications of these data are discussed. © 1994.

author list (cited authors)

  • Burgess, K., & van der Donk, W. A.

citation count

  • 8

publication date

  • June 1994