Anionic group 6 hydrides and carboxylates as homogeneous catalysts for reduction of aldehydes and ketones Academic Article uri icon

abstract

  • The catalytic reduction of aldehydes and ketones to alcohols has been successfully effected through the use of (M = Cr, W, Mo; B = Bronsted base) under hydrogen pressure in THF or Both organic and inorganic Bronsted bases have been utilized for these reactions. Mechanistic models of this process include the ligand-assisted heterolytic cleavage of H2, an alkoxide-stabilized oxidative-addition dihydride, or an group 6 metal carbonyl as intermediates which are expected to produce a highly reactive group 6 anionic hydride. Subsequent steps involve hydride attack on the carbonyl carbon followed by protonation to produce the alcohol. 1986, American Chemical Society. All rights reserved.

published proceedings

  • Journal of the American Chemical Society

author list (cited authors)

  • Tooley, P. A., Ovalles, C., Kao, S. C., Darensbourg, D. J., & Darensbourg, M. Y.

publication date

  • January 1, 1986 11:11 AM