Coherent Raman protocol of biosensing with a hollow photonic-crystal fiber Academic Article uri icon


  • A nonlinear-optical protocol of biosensing is demonstrated with a hollow-core photonic-crystal fiber. This protocol involves phase-matched four-wave mixing of millijoule nanosecond laser pulses guided by photonic band gaps of hollow fibers with a two-dimensionally periodic cladding and a core diameter of about 50 m. Raman resonances related to the stretching vibrations of water molecules inside the hollow fiber core are detected in the spectrum of the four-wave mixing signal, suggesting phase-matched coherent anti-Stokes Raman scattering in hollow photonic-crystal fibers as a convenient sensing technique for condensed-phase biospecies adsorbed on the inner fiber walls and trace gas detection, including exhale-gas diagnostics. 2005-IOS Press and the authors. All rights reserved.

published proceedings


author list (cited authors)

  • Konorov, S. O., Fedotov, A. B., Mel'nikov, L. A., Shcherbakov, A. V., Miles, R. B., & Zheltikov, A. M.

publication date

  • January 1, 2005 11:11 AM