A STIMulating journey into optogenetic engineering Academic Article uri icon

abstract

  • Genetically-encoded calcium actuators (GECAs) stemmed from STIM1 have enabled optical activation of endogenous ORAI1 channels in both excitable and non-excitable tissues. These GECAs offer new non-invasive means to probe the structure-function relations of calcium channels and wirelessly control the behavior of awake mice.

author list (cited authors)

  • Ma, G., & Zhou, Y.

citation count

  • 1

publication date

  • June 2020