A STIMulating journey into optogenetic engineering. Academic Article

abstract

• Genetically-encoded calcium actuators (GECAs) stemmed from STIM1 have enabled optical activation of endogenous ORAI1 channels in both excitable and non-excitable tissues. These GECAs offer new non-invasive means to probe the structure-function relations of calcium channels and wirelessly control the behavior of awake mice.

authors

• Ma, Guolin
• Zhou, Yubin

published proceedings

• Cell Calcium

author list (cited authors)

• Ma, G., & Zhou, Y.

citation count

• 3

complete list of authors

• Ma, Guolin||Zhou, Yubin

publication date

• January 2020

publisher

• Elsevier  Publisher

published in

• Cell Calcium  Journal

keywords

• CRAC Channel
• Calcium Signaling
• Optogenetics
• STIM1

Digital Object Identifier (DOI)

• 10.1016/j.ceca.2020.102197

start page

• 102197

end page

• 102197

volume

• 88

URL

• http://dx.doi.org/10.1016/j.ceca.2020.102197