Contemporary use of ceftaroline fosamil for the treatment of community-acquired bacterial pneumonia: CAPTURE study experience. Academic Article uri icon

abstract

  • The Clinical Assessment Program and Teflaro() Utilization Registry (CAPTURE) is a multicenter cohort study designed to collect information on the contemporary use of ceftaroline fosamil in the US. Data collected from 398 evaluable patients with community-acquired bacterial pneumonia (CABP) (mean age 64 years) during the first 18 months of the study are presented. Most patients had co-morbidities (76%; primarily structural lung disease), and 2 signs and symptoms of CABP (76%). Overall clinical success was 79% which varied little with ceftaroline fosamil usage (monotherapy vs concurrent therapy; first-line vs second-line therapy). Most patients were discharged home (60%) or to another healthcare facility (35%). These data suggest that ceftaroline, in contemporary clinical use, is an effective antibiotic for the treatment of patients with CABP, including those with significant co-morbidities or who required a change of their prior antibiotic therapy.

published proceedings

  • J Chemother

author list (cited authors)

  • Ramani, A., Udeani, G., Evans, J., Jandourek, A., Cole, P., Smith, A., & David Friedland, H.

citation count

  • 16

complete list of authors

  • Ramani, Ananthakrishnan||Udeani, George||Evans, John||Jandourek, Alena||Cole, Phillip||Smith, Alexander||David Friedland, H

publication date

  • August 2014