Lipoprotein Lipase Sorting: Sphingomyelin and a Proteoglycan Show the Way Academic Article uri icon

abstract

  • A mechanistic description for how soluble protein cargos are sorted into distinct vesicle classes at the level of the trans-Golgi network (TGN) has remained elusive. In a recent study in Developmental Cell, Sundberg et al. reveal that sphingomyelin and a proteoglycan mediate lipoprotein lipase sorting in the TGN.

author list (cited authors)

  • Bankaitis, V. A., & Wang, Y.

citation count

  • 1

publication date

  • January 2020