Sulfamic acid promoted one-pot multicomponent reaction: a facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions. Academic Article uri icon


  • We report an efficient and facile one-pot synthesis of 4-oxo-tetrahydroindoles using sulfamic acid under ball milling conditions. The present protocol for preparation of biologically important 4-oxo-tetrahydroindoles offers several advantages such as mild reaction conditions, improved selectivity and higher isolated yields. Moreover, solvent-free reaction conditions and the use of ball milling make the present protocol environmentally friendly in nature.

published proceedings

  • RSC Adv

altmetric score

  • 0.25

author list (cited authors)

  • Lambat, T. L., Abdala, A. A., Mahmood, S., Ledade, P. V., Chaudhary, R. G., & Banerjee, S.

citation count

  • 17

complete list of authors

  • Lambat, Trimurti L||Abdala, Ahmed A||Mahmood, Sami||Ledade, Pankaj V||Chaudhary, Ratiram G||Banerjee, Subhash

publication date

  • December 2019