Compositions and methods for drug sensitization of parasites Patent uri icon

abstract

  • Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof in an amount and formulation sufficient to inhibit or induce drug-sensitization in a parasite. The methods can comprise administering a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof to a parasite in an amount and formulation sufficient to inhibit or induce drug-sensitization in the parasite.

author list (cited authors)

  • Sacchettini, J. C., Miller, M. W., Wallis, D., Zhou, N. E., & Fossum, T. W.

complete list of authors

  • Sacchettini, James C||Miller, Matthew W||Wallis, Deann||Zhou, Nian E||Fossum, Theresa W

publication date

  • January 1, 2019 11:11 AM