Controlled release vaccines and methods of treating Brucella diseases and disorders Patent uri icon

abstract

  • Methods and compositions for the treatment of Brucella induced diseases and disorders are disclosed herein. In preferred embodiments, the invention relates to vaccines. In additional embodiments, the invention relates to formulations capable of releasing said vaccines at a controlled rate of release in vivo. In further embodiments, the invention relates to modified strains of the bacteria Brucella melitensis and Brucella abortus. In still further embodiments, the invention relates to compositions that do not induce clinical symptoms or splenomegaly in a subject receiving said compositions.

author list (cited authors)

  • Ficht, T. A., Ficht, A., Tsolis, R., & Garry, A. L.

complete list of authors

  • Ficht, Thomas A||Ficht, Allison||Tsolis, Renee||Garry, Adams Leslie

publication date

  • March 2019