Compositions and methods of enhancing immune responses to Eimeria Patent uri icon


  • Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.

author list (cited authors)

  • Bottje, W., Hargis, B., Berghman, L., Kwon, Y. M., Cole, K., Cox, M., ... Tellez, G.

complete list of authors

  • Bottje, Walter||Hargis, Billy||Berghman, Luc||Kwon, Young Min||Cole, Kimberly||Cox, Mandy||Layton, Sherryll||El-Ashram, Saeed||Barta, John||Tellez, Guillermo

publication date

  • July 2018