Inhibitors of activin-like receptor kinases Patent uri icon

abstract

  • The claimed invention is directed to a method for screening a compound that binds to an allosteric site of ALK2, the method comprising screening for a compound that is capable of destabilizing the ALK2 protein. A further aspect of the invention is directed to a pharmaceutical composition for the treatment and/or prophylaxis of a disease in a vertebrate, said composition comprising at least one ALK receptor kinase inhibitor, and optionally a pharmaceutically acceptable carrier, adjuvant and/or diluent.

author list (cited authors)

  • Groppe, J. C.

complete list of authors

  • Groppe, Jay Clemens

publication date

  • May 2018