Cleave and Unleash: Metacaspases Prepare Peps for Work
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Plant elicitor peptide 1 (Pep1) is a versatile immune modulator that is involved in plant defense against herbivores and pathogens. A recent study (Hander et al., Science, 2019) has uncovered that Arabidopsis thaliana Pep1 is released from the C-terminus of the tonoplast-resident precursor protein, PROPEP1, by Ca2+-activated metacaspases upon cell membrane rupture in damaged tissues.
author list (cited authors)
Hou, S., Yin, C., & He, P.