Widespread changes in transcriptome profile of human mesenchymal stem cells induced by 2D nanosilicates Conference Paper uri icon

abstract

  • © 2019 Omnipress - All rights reserved. Statement of Purpose: Two-dimensional (2D) nanomaterials, an ultrathin class of materials, have emerged as a new generation of materials due to their unique properties relative to macroscale counterparts. However, little is known about the transcriptome dynamics following exposure to these nanomaterials. Here we investigate the interactions of 2D nanosilicates, a layered clay, with human mesenchymal stem cells (hMSCs) at the whole transcriptome level by high-throughput sequencing (RNA-seq).

author list (cited authors)

  • Carrow, J. K., Cross, L. M., Reese, R. W., Jaiswal, M. K., Gregory, C. A., Kaunas, R., Singh, I., & Gaharwar, A. K.

publication date

  • January 2019