AC electrospray biomaterials synthesis. Academic Article uri icon

abstract

  • A rapid, viable and safe fabrication method for biomaterials synthesis is reported using high-frequency AC electrospraying. We demonstrate its potential for polymeric nanoparticle fabrication, drug encapsulation in mono-dispersed micron-sized biodegradable polymer shells and the synthesis of 1microm biodegradable fibers with adjustable pore sizes as bioscaffolds for tissue/orthopaedic engineering and wound care therapy. The absence of charge in the ejected drops and fibers facilitates pulmonary drug delivery, polymer encapsulation and minimizes protein/DNA denaturing or compound ionization.

published proceedings

  • Biomaterials

altmetric score

  • 3

author list (cited authors)

  • Yeo, L. Y., Gagnon, Z., & Chang, H

citation count

  • 89

complete list of authors

  • Yeo, Leslie Y||Gagnon, Zachary||Chang, Hsueh-Chia

publication date

  • November 2005