AC electrospray biomaterials synthesis. Academic Article

abstract

• A rapid, viable and safe fabrication method for biomaterials synthesis is reported using high-frequency AC electrospraying. We demonstrate its potential for polymeric nanoparticle fabrication, drug encapsulation in mono-dispersed micron-sized biodegradable polymer shells and the synthesis of 1microm biodegradable fibers with adjustable pore sizes as bioscaffolds for tissue/orthopaedic engineering and wound care therapy. The absence of charge in the ejected drops and fibers facilitates pulmonary drug delivery, polymer encapsulation and minimizes protein/DNA denaturing or compound ionization.

authors

• Gagnon, Zachary

published proceedings

• Biomaterials

altmetric score

• 3

author list (cited authors)

• Yeo, L. Y., Gagnon, Z., & Chang, H.

citation count

• 91

complete list of authors

• Yeo, Leslie Y||Gagnon, Zachary||Chang, Hsueh-Chia

publication date

• January 2005

publisher

• Elsevier  Publisher

published in

• Biomaterials  Journal

keywords

• Biocompatible Materials
• Crystallization
• Drug Carriers
• Drug Delivery Systems
• Electrochemistry
• Electromagnetic Fields
• Ions
• Nanostructures
• Nanotechnology
• Particle Size
• Polymers

Digital Object Identifier (DOI)

• 10.1016/j.biomaterials.2005.03.033

start page

• 6122

end page

• 6128

volume

• 26

issue

• 31

URL

• http://dx.doi.org/10.1016/j.biomaterials.2005.03.033