Effects of micro-osteoperforations on tooth movement and bone in the beagle maxilla. Academic Article uri icon


  • PURPOSE: The purpose of this study was to determine how micro-osteoperforations (MOPs) affect tooth movements, bone turnover, bone density, and bone volume. METHODS: A split-mouth experimental design with 7 beagle dogs was used to evaluate bone surrounding maxillary second premolars that had been retracted for 7weeks. One month after the maxillary third premolars were extracted, 8 MOPs (1.5mm wide and 7mm deep) were created without flaps with the use of the Propel device (6 were placed 3mm distal to the second premolar and 2 were placed in the premolar furcation) on one randomly chosen side. The maxillary second premolars were retracted bilaterally with the use of 200g nickel-titanium closed coil springs. Tooth movements were measured intraorally and radiographically. Microscopic computed tomography was used to evaluate the material density and volume fraction of bone distal to the premolars. Hematoxylin and eosin-stained and fluorescent sections were used to examine the bone remodeling. RESULTS: Neither the intraoral (P=0.866) nor radiographic (P=0.528) measures showed statistically significant side differences in tooth movements. There also were no statistically significant differences in the density (P=0.237) or volume fraction (P=0.398) of bone through which the premolars were being moved. Fluorescent and histologic evaluations showed no apparent differences in osteoblasts, osteoclasts, or mineralization of bone near the teeth being moved. Bone healing was evident in and near the MOP sites, which had nearly but not completely healed after 7weeks. Regions of acellular bone were evident extending 0.8mm from the MOP sites. CONCLUSIONS: MOPs placed 3mm away from teeth do not increase tooth movements and have limited and transitory effect on bone.

published proceedings

  • Am J Orthod Dentofacial Orthop

author list (cited authors)

  • Cramer, C. L., Campbell, P. M., Opperman, L. A., Tadlock, L. P., & Buschang, P. H.

citation count

  • 14

complete list of authors

  • Cramer, Chris L||Campbell, Phillip M||Opperman, Lynne A||Tadlock, Larry P||Buschang, Peter H

publication date

  • May 2019