Individual variation in 3-methylbutanal: a putative link between human leukocyte antigen and skin microflora. Academic Article

abstract

• The human derma emits volatile compounds whose interaction with a receiver's olfactory sensory system may affect individual recognition and mating preferences. Studies suggest that both genes and environmental factors determine characteristic odor of an individual. We used solid-phase microextraction and gas chromatography-mass spectrometry to identify 3-methylbutanal in human axillary odor; we showed that the abundance of this volatile compound varies significantly among individuals and demonstrated that its formation in vitro may be influenced by interaction between human leukocyte antigen peptide and dermal microflora.

authors

• Antony Babu, Sanjay

published proceedings

• J Chem Ecol

author list (cited authors)

• Savelev, S. U., Antony-Babu, S., Roberts, S. C., Wang, H., Clare, A. S., Gosling, L. M., ... Ward, A. C.

citation count

• 18

complete list of authors

• Savelev, Sergey U||Antony-Babu, Sanjay||Roberts, S Craig||Wang, Huitu||Clare, Anthony S||Gosling, L Morris||Petrie, Marion||Goodfellow, Michael||O'Donnell, Anthony G||Ward, Alan C

publication date

• September 2008

publisher

• Springer Nature  Publisher

published in

• Journal of Chemical Ecology  Journal

keywords

• Adult
• Aldehydes
• Analysis Of Variance
• Female
• Gas Chromatography-Mass Spectrometry
• HLA Antigens
• Humans
• Male
• Odorants
• Skin

PubMed Central ID

• 18668292

Digital Object Identifier (DOI)

• 10.1007/s10886-008-9524-1

start page

• 1253

end page

• 1257

volume

• 34

issue

• 9

URL

• http://dx.doi.org/10.1007/s10886-008-9524-1