Flavin-N5-oxide intermediates in dibenzothiophene, uracil, and hexachlorobenzene catabolism. Chapter uri icon

abstract

  • Flavin-N5-oxide is a new intermediate in flavoenzymology. Here we describe the identification of DszA (dibenzothiophene catabolism), RutA (uracil catabolism) and HcbA1 (hexachlorobenzene catabolism) as flavin-N5-oxide-utilizing enzymes. Mechanistic analysis of these reactions suggests a model for the identification of other examples of this catalytic motif.

author list (cited authors)

  • Adak, S., & Begley, T. P.

complete list of authors

  • Adak, Sanjoy||Begley, Tadhg P

Book Title

  • NEW APPROACHES FOR FLAVIN CATALYSIS

publication date

  • January 1, 2019 11:11 AM