n397420SE Academic Article uri icon


  • We report a plasmonic paper-based analytical platform with functional versatility and subattomolar (<10(-18) M) detection limit using surface-enhanced Raman scattering as a transduction method. The microfluidic paper-based analytical device (PAD) is made with a lithography-free process by a simple cut and drop method. Complex samples are separated by a surface chemical gradient created by differential polyelectrolyte coating of the paper. The PAD with a starlike shape is designed to enable liquid handling by lateral flow without microchannel patterning. This design generates a rapid capillary-driven flow capable of dragging liquid samples as well as gold nanorods into a single cellulose microfiber, thereby providing an extremely preconcentrated and optically active detection spot.

published proceedings

  • Anal Chem

author list (cited authors)

  • Abbas, A., Brimer, A., Slocik, J. M., Tian, L., Naik, R. R., & Singamaneni, S.

publication date

  • January 1, 2013 11:11 AM