Controlled bacteria-gold nanorod interactions for enhancement of optoacoustic contrast Conference Paper uri icon


  • Gold-based contrast agents, gold nanorod (GNR), were designed for the enhancement of optoacoustic signal. After synthesis, the GNR-CTAB complexes were modified by pegylation (PEG), or replacement of CTAB (cetyl trimethylammonium bromide) with MTAB (16-mercaptohexadecyl trimethylammonium bromide) for coverage of gold nanorods with heparin (GNR-HP). Modified GNR are purified through centrifugation and filtration. GNRCTAB can be used as a model of positively charged gold surface for quantitative optoacoustic sensing in GNRbacteria interactions, whereas GNR-PEG and GNR-HP can be used as negatively charged gold surface models. We studied controlled agglomeration of contrast agents with the bacteria E.Coli and Vibrio Cholerae. For bacterial sensing, the localized plasmon resonance peak shifts as a function of electrostatic binding, which was detected with two different wavelengths through 3D optoacoustic imaging.

name of conference

  • Photons Plus Ultrasound: Imaging and Sensing 2014

published proceedings

  • Proceedings of SPIE

altmetric score

  • 3

author list (cited authors)

  • Liopo, A., Derry, P. J., Ermolinsky, B., Su, R., Conjusteau, A., Ermilov, S., Zubarev, E. R., & Oraevsky, A.

citation count

  • 2

complete list of authors

  • Liopo, Anton||Derry, Paul J||Ermolinsky, Boris||Su, Richard||Conjusteau, AndrĂ©||Ermilov, Sergey||Zubarev, Eugene R||Oraevsky, Alexander

editor list (cited editors)

  • Oraevsky, A. A., & Wang, L. V.

publication date

  • January 2014