Fast and minimally-invasive tumor margin detection using a novel micromachined side-viewing oidrs sensor probe Conference Paper uri icon


  • 2010TRF. In this paper, we report the design, fabrication and testing of a novel miniaturized optical sensor probe with side-viewing capability. Its unprecedented small size, unique side-viewing capability and high optical transmission efficiency enable the agile maneuvering and efficient data collection even in the narrow cavities inside the human body. The sensor probe consists of four micromachined substrates with optical fibers for oblique light incidence and collection of spatially resolved diffuse reflectance from the contacted tissues. The optical sensor probe has been used to conduct the oblique incidence diffuse reflectance spectroscopy (OIDRS) on a human pancreatic specimen. Based on the measurement results, the margin of the malignant tumor has been successfully determined optically, which matches well with the histological results.

published proceedings

  • Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop

author list (cited authors)

  • Chang, C. C., Garcia-Uribe, A., Zou, J., Wang, L. V., Banerjee, B., & Kuczynski, J.

complete list of authors

  • Chang, CC||Garcia-Uribe, A||Zou, J||Wang, LV||Banerjee, B||Kuczynski, J

publication date

  • January 2010