Micromachined side-viewing optical sensor probe for no-invasive detection of esophageal cancers
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2008 TRF. In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with side viewing capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of three micromachined positioning substrates and source/collection fibers to achieve 45 o light incidence and collection of spatial resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for classification of cancerous tissues from normal ones for the first time.