Creation of artificial cellulosomes on DNA scaffolds by zinc finger protein-guided assembly for efficient cellulose hydrolysis.
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For the first time, artificial cellulosome structures were created on DNA scaffolds based on zinc finger protein (ZFP)-guided assembly. These resulting two-component cellulosome structures exhibited enhancement in cellulose hydrolysis compared to the non-complexed mixture depending on the number of CBMs and cellulases assembled.
author list (cited authors)
Sun, Q., Madan, B., Tsai, S., DeLisa, M. P., & Chen, W.
complete list of authors
Sun, Qing||Madan, Bhawna||Tsai, Shen-Long||DeLisa, Matthew P||Chen, Wilfred